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4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Basic Information
- CAS No.: 21928-50-7
Physical properties
Product Description
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1.What is the 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol ?
4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-piperidinol may be used to synthesize piperidinols and penfluridol (a neuroleptic agent).
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863111-54-0
tert-butyl 4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxypiperidine-1-carboxylate
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21928-50-7
4-[4-chloro-3-trifluoromethylphenyl]-4-piperidinol
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
ethanol;
at 50 ℃;
for 16h;
|
68%
|
|
With
hydrogenchloride;
In
ethyl acetate;
at 20 ℃;
|
|
|
With
hydrogenchloride;
In
methanol;
|
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-
21928-40-5
1-ethoxycarbonyl-4-(3-trifluoromethyl-4-chlorophenyl)-4-piperidinol
-
-
21928-50-7
4-[4-chloro-3-trifluoromethylphenyl]-4-piperidinol
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
ethanol;
for 3.5h;
Reflux;
|
94%
|
2.What is the CAS number for 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol ?
The CAS number of 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol is 21928-50-7.
More information of 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol 21928-50-7 are:
|
CAS?Number |
21928-50-7 |
|
Density |
1.347 g/cm3 |
|
Melting Point |
138-141 °C(lit.) |
|
Boiling Point |
333.3 °C at 760 mmHg |
|
Flash Point |
155.4 °C |
|
Vapor Pressure |
5.48E-05mmHg at 25°C |
|
HS CODE |
29333999 |
|
PSA |
32.26000 |
|
LogP |
3.25860 |
|
Pka |
13.55±0.20(Predicted) |
3.What are another words for 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol ?
Synonyms?for?4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol 21928-50-7:4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol;4-Piperidinol,4-(4-chloro-a,a,a-trifluoro-m-tolyl)- (8CI);4-(3-Trifluoromethyl-4-chlorophenyl)-4-piperidinol;4-(4-Chloro-3-trifluoromethylphenyl)-4-hydroxypiperidine;4-Hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine;4-Hydroxy-4-(4-chloro-3-trifluoromethylphenyl)piperidine;4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol;4'-(4-Chloro-3-trifluoromethylphenyl)-4'-hydroxypiperidine;
4.What is the molecular formula of 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol?
The chemical formula of ?4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol is?C12H13ClF3NO which containing 12 Carbon atoms,13 Hydrogen atoms,1 Chlorine atoms,3 Fluorine atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol?is 279.69.
5.What is 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol (21928-50-7) used for?
4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol is a beige fine crystalline powder with a complex chemical structure. It is a derivative of piperidinol, featuring a 4-chloro-3-(trifluoromethyl)phenyl group attached to its piperidinol backbone. 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol is known for its potential applications in the pharmaceutical industry, particularly in the synthesis of various medications.
InChI:InChI=1/C12H13ClF3NO/c13-10-2-1-8(7-9(10)12(14,15)16)11(18)3-5-17-6-4-11/h1-2,7,17-18H,3-6H2/p+1
Relevant articles related to 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol:
|
Article |
Source |
|
Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity |
Ashraf-Uz-Zaman, Md,Sajib, Md Sanaullah,Cucullo, Luca,Mikelis, Constantinos M.,German, Nadezhda A. supporting information, p. 3652 - 3657 (2018/11/03) |
|
Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers |
Chen, Gang,Xia, Hongguang,Cai, Yu,Ma, Dawei,Yuan, Junying,Yuan, Chengye scheme or table, p. 234 - 239 (2011/02/26) |
6.Buy 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol with the best price .
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