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SULFAMETHIZOLE
Basic Information
- CAS No.: 144-82-1
Physical properties
Product Description
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1.What is the SULFAMETHIZOLE ?
Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC en zyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.
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39719-87-4
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide
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144-82-1
sulfamethizole
| Conditions | Yield |
|---|---|
|
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide;
With
hydrogenchloride;
In
water;
for 0.5h;
Reflux;
With
sodium carbonate;
In
water;
|
72%
|
|
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide;
With
hydrogenchloride;
In
water;
for 0.5h;
Reflux;
With
sodium carbonate;
In
water;
|
72%
|
|
With
hydrogenchloride;
|
|
|
With
sodium hydroxide;
|
-
-
349621-24-5
N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-nitrobenzenesulfonamide
-
-
144-82-1
sulfamethizole
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
iron;
In
ethanol; water;
for 3h;
Reflux;
|
100%
|
2.What is the CAS number for SULFAMETHIZOLE ?
The CAS number of SULFAMETHIZOLE is 144-82-1.
More information of SULFAMETHIZOLE 144-82-1 are:
|
CAS?Number |
144-82-1 |
|
Density |
1.562g/cm3 |
|
Melting Point |
208 - 210 C |
|
Boiling Point |
504.9°Cat760mmHg |
|
Flash Point |
259.1°C |
|
Vapor Pressure |
2.56E-10mmHg at 25°C |
|
Refractive Index |
1.6440 (estimate) |
|
HS CODE |
2935904000 |
|
PSA |
134.59000 |
|
LogP |
2.96450 |
|
Pka |
5.45(at 25℃) |
3.What are another words for SULFAMETHIZOLE ?
Synonyms?for?SULFAMETHIZOLE 144-82-1:Sulfanilamide,N1-(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,7CI,8CI); 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole;2-Sulfanilamido-5-methyl-1,3,4-thiadiazole;4-Amino-N-(5-methyl-[1,3,4]thiadiazol-2-yl)benzenesulfonamide;5-Methyl-2-sulfanilamido-1,3,4-thiadiazole; Ayerlucil; Famet; Lucosil;Methazol; Microsul; N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-aminobenzenesulfonamide;N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; Renasul; Rufol; Salimol;Sulfamethiazole; Sulfamethizol; Sulfamethizole; Sulfamethylthiadiazole;Sulfapyelon; Sulfstat; Sulfurine; Sulphamethizole; Tetracid; Thidicur;Thiosulfil; Thiosulfil Forte; Ultrasul; Urocydal; Urodiaton; Urolucosil;Urosulfin; VK 53
4.What is the molecular formula of SULFAMETHIZOLE?
The chemical formula of ?SULFAMETHIZOLE is?C9H10 N4 O2 S2 which containing 9 Carbon atoms,10 Hydrogen atoms,4 Nitrogen atoms,2 Oxygen atoms and 2 Sulfur atoms,and the molecular weight of??SULFAMETHIZOLE?is 270.336.
5.What is SULFAMETHIZOLE (144-82-1) used for?
Sulfamethizole is a broad spectrum sulfonamide antibiotic (MIC90s = 1.25-5,000 μg/ml against clinical isolates of E. coli and K. pneumoniae). It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract infections.
InChI:InChI=1/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
Relevant articles related to SULFAMETHIZOLE:
|
Article |
Source |
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MODULATORS OF IMMUNOINHIBITORY RECEPTOR PD-1, AND METHODS OF USE THEREOF |
- Page/Page column 52, (2011/07/30) |
|
Process for formulating a synthetic drug for use in animal feed, and resulting formulation |
- , (2008/06/13) |
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